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FAN, ZHEN
One or more keywords matched the following items that are connected to FAN, ZHEN
Item TypeName
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Academic Article The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression.
Academic Article Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.
Academic Article The anti-EGFR antibody cetuximab sensitizes human head and neck squamous cell carcinoma cells to radiation in part through inhibiting radiation-induced upregulation of HIF-1a.
Academic Article Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha.
Academic Article Requirement of hypoxia-inducible factor-1alpha down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab.
Academic Article Cetuximab reverses the Warburg effect by inhibiting HIF-1-regulated LDH-A.
Academic Article The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex.
Academic Article AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab.
Academic Article Overcoming cisplatin resistance of ovarian cancer cells by targeting HIF-1-regulated cancer metabolism.
Academic Article Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.
Academic Article Functional cooperation between HIF-1a and c-Jun in mediating primary and acquired resistance to gefitinib in NSCLC cells with activating mutation of EGFR.
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  • Hypoxia Inducible Factor 1 alpha Subunit